Pharmaceutical, compositions containing substituted 4'-hydroxyph

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 31155

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active

041090144

ABSTRACT:
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.

REFERENCES:
chem. Abst., vol. 29, col. 1504(8), (1935).
Chem. Abst., vol. 47, col. 3923(b), (1953).

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