Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1977-01-25
1978-08-22
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31155
Patent
active
041090144
ABSTRACT:
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
REFERENCES:
chem. Abst., vol. 29, col. 1504(8), (1935).
Chem. Abst., vol. 47, col. 3923(b), (1953).
Hughes John Lawrence
Liu Robert Chung-Huan
Armour Pharmaceutical Company
Barber Frank T.
Meyers Albert T.
Mybeck Richard R.
Stephens Daren M.
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