Pharmaceutical compositions, containing S-adenosyl-L-methionine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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514249, 514254, 514269, 514885, A61K 317105

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active

060937033

ABSTRACT:
For the therapy of neurological complications in AIDS sufferers, the use of pharmaceutical compositions containing as an active principle at least one compound selected from the group consisting of S-adenosyl-L-methionine salt, 5-methyl-tetrahydro-folic acid, 5-formyltetrahydro-folic acid, when the active principle consists of S-adenosyl-L-methionine and of a derivative of tetrahydro folic acid, the weight ratio between the S-adenosyl-L-methionine salt and 5-methyltetrahydrofolic acid or 5-formyl-tetrahydrofolic acid is comprised between 10/1 and 4/1, in pharmaceutical form, suitable for oral or parenteral administration.

REFERENCES:
patent: 5059595 (1991-10-01), Le Grazie
Budavari et al, eds, (1989) The Merck Index, Merck & Co., Inc., New Jersey, pp 456-457, Eleventh Edition.
115 CA:223447v Grundmann et al. 1991.
90 CA: 3493g (3493g) Balk et al 1979.
114 CA: 75184u Jacob et al 1991.

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