Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-03-20
1999-12-21
Spivack, Phyllis G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31505
Patent
active
060049685
ABSTRACT:
The present invention relates to pharmaceutical formulations containing (2R, cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2 -one (-)-2',3'-dideoxy,3'-thiacytidine, lamivudine, that are substantially free of ethanol and ethylenediamine-tetraacitic acid, and their use in medical therapy.
REFERENCES:
patent: 5047407 (1991-09-01), Belleau et al.
patent: 5859021 (1999-01-01), Cameron et al.
Casey et al., J. Pharmaceutical Science and Technology, 50(6), 352-355, Nov. 12, 1996.
Nguyen et al., Drug Development and Industrial Pharmacy, 21(14), 1671-1682, Jul. 1995.
Warren M. Casey, et. al., "Use of the Green Fluorescent Protein to Rapidly Access Viability of E coli Preserved Resolutions," PDA Journal of Pharmaceutical Science & Technology, vol. 50, No. 6 / Nov.-Dec. 1996, pp. 352-355.
Mickey L. Wells, et., al., "Formulation of a Preservative System Using Pass/Fail Data," PT 6177, Pharmaceutical Research, 10(10) S171 (1993).
Warren M. Casey, et al., "Use of the Green Fluorescent Protein to Rapidly Assess Viability of E coli Preserved Resolutions," PDA (International Association for Pharmaceutical Science and Technology) 1996 Annual Meeting Courses, and Exhibit, Pharmaceutical Manufacturing & Technology: Past, Present & Future, Nov. 18-22, 1996, Phila., PA, pp. 18-19.
Ngoc-Anh T. Nguyen, et. al., "Identification of Factors Affecting Preservative Efficacy and Chemical Stability of Lamivudine Oral Solution Through Statistical Experimental Design," Drug Development and Industrial Pharmacy, 21(14), pp. 1671-1682 (1995).
Casey Warren Michael
Nguyen Ngoc-Anh Thi
Glaxo Wellcome Inc.
Prus Karen L.
Spivack Phyllis G.
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