Pharmaceutical compositions containing hollow fine tubular drug

Details Pharmaceutical compositions containing hollow fine tubular drug Pharmaceutical compositions containing hollow fine tubular drug

1985-05-03

1987-06-16

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

514965, A61K 900

Patent

active

046735658

ABSTRACT:
Pharmaceutical compositions are provided which contain hollow fine tube drug delivery systems. The compositions comprise a pharmaceutically suitable carrier, preferably in the form of a capsule, tablet, suspension, or suppository, and at least one drug delivery system which consists essentially of (1) a polymeric tube having a membrane outer sheath and a hollow core, and (2) at least one drug compound contained within the core, said system contained in the composition in an amount sufficient to deliver a therapeutic amount of the drug contained therein at a predetermined rate over a predetermined period of time. By varying the polymer, the permeability of the outer sheath, the drug, the drug concentration in the hollow core of the tube, the tube diameter, the tube length, the tube core diameter, and the sealing of the tube ends, a wide variety of drug therapeutic amounts, rates and dosing times can be achieved.

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Controlled Release Society Meeting, Jul. 23-25, 1984, Ft. Lauderdale, FL.

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