Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1997-12-29
2000-08-22
Lankford, Jr., Leon B.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
424404, 424405, 424439, 426 2, 426 53, 426489, 426542, 426651, 426655, 514885, A61K 3578, A01N 2500, A23L 1222
Patent
active
061068381
DESCRIPTION:
BRIEF SUMMARY
FIELD OF THE INVENTION
The present invention relates to the preparation of various forms of pharmaceuticals for medical and veterinary uses, said pharmaceuticals comprising as active ingredients special herbal essences, capable of substituting antibiotics and sulphamide based drugs, due to their important activity against germs causing inflammations, infections and diarrhoea in humans and animals.
DESCRIPTION OF RELATED ART
The presently used methods for treatment of inflammations, infections and diarrhoea in humans and animals rely on the use of pharmaceuticals that contain antibiotics and sulphamides. It is known that these pharmaceuticals are often the cause of severe short and long term side effects, for example the accumulation of bioresidues. In addition, microorganisms that are to be combatted by these pharmaceuticals develop with time a resistance to these drugs, thus reducing the efficiency of the treatment.
This is because the living organism of humans or animals is incapable of fully assimilating or rejecting these chemicals, resulting in accumulation of chemical in the organism and causing serious side effects exemplified by hereditary changes or sensitivity to microorganisms against which these chemicals had been used.
It is to be noted that animals are more subjected to frequent use of antibiotics than humans. It is known that antibiotics against infections and inflammations are regularly administered on a daily basis to livestock by enrichment of livestock foodstuffs (poultry dough) to prevent diarrhoea and coccidiosis.
This is because in their effort to preserve their livestock capital from infectious, inflammatory and diarroeic diseases, stock-farmers inconsiderately resort to frequent use of these pharmaceuticals and this practice, although helpful in the treatment of said diseases, results in consumer products being charged with elevated quantities of antibiotics.
The situation in humans is to a lesser extent but equally alarming, as many deaths are reported that are caused by prolonged treatment with antibiotics.
BACKGROUND OF THE INVENTION
The present invention refers to compositions containing essential oils that are as effective against inflammations, infections and diarrhoea as antibiotics and sulphamides, but differ essentially from the latter (and this is due to the herbal origin of these essential oils) in that they are fully assimilable or rejectable by the living organism, thus avoiding bioresidues and side effects.
These substances originating from herbal essences, in admixture with inert substances according to methods that are described below, constitute the essential ingredients of pharmaceutical compositions for medical and veterinary use, said compositions having properties of full and effective prevention of and treatment of various inflammations, infections and diarrhoea, while being safe for the environment and the organism (human or animal).
The substances that constitute the essential ingredient of said pharmaceutical compositions which are one of the objects of the present inventions are herbal essences with high contents in thymol, carvacrol and tannin.
These substances can all be obtained from herbs like Thymus vulgaris, thymus serpilum, saturea hortensis, saturea montana, saturea subricata, carum coptimum(India), thymus zygus (Spain), ocimum gratisum (Southern France and Africa), moranda puntata (North America), mosia japanoica maxinowisz (Japan), salvia officiaiatis and the like.
Herbs of the Labiatae family, which have been widely used as spices for flavouring dishes and beverages, are known to contain high amounts of thymol and carvacrol. The most common among them, thyme and oregano, differ from each other mainly in the content ratio of thymol and carvacrol. The essential oil obtained from thyme, which is known to possess antifungal and antimicrobial activity, has a higher content in thymol; on the contrary, herbs of the genus origanum contain predominantly carvacrol.
It was found that thymol alone as well as essential oils containing thymol in amounts
REFERENCES:
Baser et al. J. Essent. Oil Res. vol. 5 (6), pp. 616-623 (abstract enclosed), 1993.
Lagouri et al. Zeitschrift fuer Leensmittel Unter. und Fors. vol. 197 (1), pp. 20-23, 1993.
Akguel et al. Nahrung. vol. 32 (2), pp. 201-203, 1988.
Sarer et al. Planta Med. vol. 46 (4), pp. 236-239 (abstract enclosed), 1982.
Van den Broucke et al. Planta Med. vol. 38 (3), pp. 264-266 (abstract enclosed), 1980.
Assaf et al. Planta Med. vol. 53 (4), pp. 343-345 (abstract enclosed), 1987 .
Lankford , Jr. Leon B.
Tate Christopher R.
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