Pharmaceutical compositions containing giroxina and phospholipas

Details Pharmaceutical compositions containing giroxina and phospholipas Pharmaceutical compositions containing giroxina and phospholipas

1994-11-15

1997-10-14

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Extract, body fluid, or cellular material of undetermined...

Derived from snake

424 946, 435198, A61K 3558, A61K 3846, C12N 920

Patent

active

056769741

ABSTRACT:
Pharmaceutical compositions for treatment of humans suffering from the symptoms of acquired immune deficiency syndrome (AIDS) or its precursors, lymphadenopathy syndrome (LAS) or AIDS-related complex (ARC) or secondary diseases relating thereto and other immunodeficiency pathologies or tumors resulting exclusively from immune deficiency and others such as H.I.V. The compositions contain a therapeutically active amount of phospholipase A.sub.2 and giroxina, preferably where the phospholipase A.sub.2 is isolated from the venom of Crotalus durissus terrificus or form the venom of Micrurus frontalis altirostris and the giroxina is isolated from the venom of Crotalus durissus terrificus. Also disclosed is the process for preparing such pharmaceutical composition and the process for treating patients suffering from the aforementioned afflictions.

REFERENCES:
patent: 4341762 (1982-07-01), Haast
patent: 5164196 (1992-11-01), Plata et al.
patent: 5354677 (1994-10-01), Knopf et al.

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