Pharmaceutical compositions containing furan derivatives

Details Pharmaceutical compositions containing furan derivatives Pharmaceutical compositions containing furan derivatives

1994-03-22

1995-10-10

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Carbonate

424717, 514184, 514471, 514503, A61K 3300, A61K 31555, A61K 3134, A61K 3129

Patent

active

054569257

ABSTRACT:
The invention relates to a pharmaceutical composition in solid unit dosage form adapted for oral administration, comprising a salt formed between ranitidine and a complex of bismuth with a carboxylic acid selected from tartaric acid and citric acid together with an alkaline salt. For example the composition is in tablet form and comprises ranitidine bismuth citrate and sodium carbonate.
The composition shows improved disintegration and/or dissolution.

REFERENCES:
patent: 4608257 (1986-08-01), Teeter
patent: 5008256 (1991-04-01), Clitherow
patent: 5013560 (1991-05-01), Stentz et al.
patent: 5064857 (1991-11-01), Bertholdt et al.
patent: 5102665 (1992-04-01), Schaeffer
Goodman et al., The Pharmacological Basis of Therapeutics, 7th edition (1986) pp. 980-987.

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