Pharmaceutical compositions containing calcitonin in a spray dos

Details Pharmaceutical compositions containing calcitonin in a spray dos Pharmaceutical compositions containing calcitonin in a spray dos

1999-03-01

2000-11-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424434, A61K 912

Patent

active

061498939

ABSTRACT:
Pharmaceutical compositions for intranasal administration containing in a spray dosing feeder calcitonin dissolved in a substantially physiological solution of sodium chloride adjusted to a pH between 3.5 and 4.5 with citrate buffer and hydrochloric acid without any preservative are the object of the present invention.

REFERENCES:
patent: 5514365 (1996-05-01), Mardente et al.
patent: 5756071 (1998-05-01), Mattern et al.
patent: 5792469 (1998-08-01), Tipton et al.
Gomori, G. Preparation of buffers for use in enzyme studies in Methods in Enzymology, vol. 1, 1955. S.P. Colowick and N.O. Kaplan eds. Academic Press, N.Y. pp. 138-146.

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