Pharmaceutical compositions containing bretazenil and methods of

Details Pharmaceutical compositions containing bretazenil and methods of Pharmaceutical compositions containing bretazenil and methods of

1991-11-27

1993-06-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514923, A61K 3155

Patent

active

052216721

ABSTRACT:
The compound t-butyl (S)-8-bromo-11,12,13,13a-tetrahydro-9-oxo-9H-imidazo[1,5-a]pyrrolo[2,1-c][ 1,4]benzodiazepine-1-carboxylate of the formula ##STR1## can be used for the preparation of medicaments for the treatment of sleep disorders and also as a medicament for the treatment of sleep disorders.

REFERENCES:
patent: 4352815 (1982-10-01), Hunkeler et al.
patent: 4353827 (1982-10-01), Hunkeler et al.
patent: 4861772 (1989-08-01), Merz
patent: 4914095 (1990-04-01), Merz
Saletu, et al., Int. J. Clin. Pharmacol. Ther. and Toxicol., vol. 27, No. 2 (1989).
Belzung, et al., Psychopharmacolog, vol. 97, 338-391 (1989).
Schreur, et al., Society for Neuroscience Abstracts, vol. 15, No. 2, (1989).
Pieri, et al., Drugs of the Future, vol. 13, No. 8 730-735 (1988).
Berkow, et al., The Merck Manual, 1376-1377 (1987).

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