Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl

Details Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl Pharmaceutical compositions containing 5-phenyl-1,3-dioxoalkenyl

1986-11-07

1988-08-02

Reamer, James H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568306, 564169, 560 51, 560 53, C07C 4546

Patent

active

047615036

ABSTRACT:
This invention relates to pharmaceutical compositions containing a class of 5-phenyl-1,3-dioxoalkenyl compounds useful as inhibitors of leukotriene biosynthesis and thus useful in the treatment of conditions associated with leukotrienes. This invention also relates to the use of the 5-phenyl-1,3-dioxoalkenyl compounds in the inhibition of leukotriene biosynthesis and thus in the treatment of conditions associated with leukotrienes. This invention further relates to a novel process for the preparation of the 5-phenyl-1,3-dioxoalkenyl compounds.

REFERENCES:
patent: 3578702 (1971-05-01), Snapp et al.
patent: 3759929 (1973-09-01), Klotmann
patent: 4521629 (1985-06-01), Cortese et al.
Lehnert, Tetrahedrod, vol. 28, pp. 663-666 (1972).

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