Pharmaceutical compositions containing 2-aryltetraazaindenes for

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514249, 544236, 544350, A61K 31495, C07D48700

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active

045755051

ABSTRACT:
2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CH.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or trisubstituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologially acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.

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patent: 4327100 (1982-04-01), Austel et al.
patent: 4477454 (1984-10-01), Jonas et al.
Mitsuji et al., Chem. Abstract, 73 (1970), 98885x.
Yanai et al., Chem. Abst. 73:98885x, (1970).
Jonas et al., Chem. Abst. 100:68323w, (1984).
J. Het. Chem. 1, 182-185, (1964), Malm et al.

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