Pharmaceutical compositions comprising tetrahydropyrimidine deri

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514269, A61K 31505

Patent

active

057894140

ABSTRACT:
A pharmaceutical composition comprising as active ingredients at least two tetrahydropyrimidine derivatives selected from (a) thereof, and (b) 2-methyl-4-carboxy-5-hydroxy-3,4,5,6-tetrahydropyrimidine pharmaceutically acceptable carrier.

REFERENCES:
patent: 4261995 (1981-04-01), Weinhardt et al.
Inbar et al, J. Bacteriol, 170, 4055 (1988).
Inbar et al, J. Biol. Chem. 263, 16014-16022 (1988).
Inbar et al, J. Bacteriol. 173 7790 (1991).
Okuda et al, Chem. Abstracts, vol. 113-129062 (1990).
Livia Inbar and Aviva Lapidot, "Metabolic Regulation in Streptomyces parvulus during Actinomycin D Synthesis, Studied with .sup.13 C-and .sup.15 N-Labeled Precursors by .sup.13 C and .sup.15 N Nuclear Magnetic Resonance Spectroscopy and by Gas Chromatography-Mass Spectrometry", Journal of Bacteriology, Sep. 1988, pp. 4055-4064, Copyright 1988, American Society for Microbiology, vol. 170. No. 9.
Petra Peters, E.A. Galinski and H.G. Truper, "The biosynthesis of ectoine", FEMS Microbiology Letters 71 (1990) 157-162, Published by Elsevier, pp. 157-162.
Galinsky, et al., "1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid A novel cyclic amino acid from halophilic phototrophic bacteria of the genus Ectothiorhodospira", pp. 135-139. (no year) Journal? vol. ?.
Erwin A. Galinski and Karin Lippert, "Novel Compatible Solutes And Their Potential Application As Stabilizers In Enzyme Technology", General and Applied Aspects of Halophilic Microorganisms, New York 1991, pp. 351-358.
Ronit Regev, et al., "C NMR Study of the Interrelation between Synthesis and Uptake of Compatible Solutes in Two Moderately Halophilic Eubacteria", Archives of Biochemistry and Biophysics, vol. 278, No. 1, Apr., pp. 106-112. no year.
Stephen C. Brown, ET AL., "Aqueous Solution Structure of an Intercalated Actinomycin D-dATGCAT Complex by Two-Dimensional and One-Dimensional Proton NMR", Biochemistry 1984, pp. 403-408.
Erwin A. Galinski, ET AL., "The Crystal Structure of Extoine, a Novel Amino Acid of Potential Osmoregulatory Function", pp. 780-784. vol. 3 no year, Journal?.
Axel Wohlfarth, ET AL., "The spectrum of compatible solutes in heterotrophic halophilic eubacteria of the family Halomonadaceae", Journal of General Microbiology (1990), pp. 705-712, printed in Great Britain.
Terry P. Lybrand, ET AL., "Computer Modeling of Actinomycin D Interactions with Double-helical DNA", J. Mol. Biol. (1986) 191, pp. 495-507. of Multiple Complexes", Biochemistry 1989, 28, pp. 5231-5239.
V.V. Nosikov, et al., "Protection of particular cleavage sites of restriction endonucleases by distamycin A and actinomycin D", Nuclear Acids Research, vol. 3, No. 9, Sep. 1976, pp. 2293-2301.
L. Inbar and A. Lapidot, ".sup.13 C Nuclear Magnetic Resonance and Gas Chromatography-Mass Spectrometry Studies of Carbon Metabolism in the Actinomycin D Producer Streptomyces parvulus by Use of .sup.13 C-Labeled Precursors", Journal of Bacteriology, Dec. 1991, pp. 7790-7801.
Henry G. Hodo III and Stanley P. Blatti, "Purification Using Polyethylenimine precipitation and Low Molecular Weight Subunit Analyses of Calf Thymus and Wheat Germ DNA-Dependent RNA Polymerase II" pp. 2334-2343, Biochemistry, vol. 16, No. 11, 1977.
Livia Inbar and Aviva Lapidot, "The Structure and Biosynthesis of New Tetrahydropyrimidine Derivatives in Actinomycin D Producer Streptomyces parvulus", pp. 16014-16022, The Journal of Biological Chemistry, vol. 263, No. 31 Issue of Nov. 5, 1988.
Patent Abstracts of Japan, unexamined applications, C field, vol. 14, No. 310, Jul. 4, 1990. The Patent Office Japanese Government, p. 40 c 736, No. 2-104 577 (Koei Chem).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pharmaceutical compositions comprising tetrahydropyrimidine deri does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions comprising tetrahydropyrimidine deri, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions comprising tetrahydropyrimidine deri will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1177449

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.