Pharmaceutical compositions comprising modified and unmodified p

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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424 9463, 514 2, 435212, 435215, A61K 3754, A61K 37547, C12N 948, C12N 972

Patent

active

054097002

ABSTRACT:
The present invention relates to pharmaceutical compositions comprising a combination of two different plasminogen activators which are used for the prophylaxis and therapie of thrombosis.

REFERENCES:
Collen et al. (1987) Amer. J. Cardiol. 60, 431-434.
Pierard et al. (1987) J. Biol. Chem. 262, 11771-11778.
Lee et al. (1988) J. Biol. Chem. 263, 2917-2924.
Pennica et al. (1983) Nature 301, 214-221.
Holmes et al. (1985) Bio/Technology 3, 923-929.
Collen et al., Circulation, 74:838.varies.842 (1986).
Collen, Circulation, 77:731-735 (1989).
Verstraete, Klin. Wochenschr., 66:5-14 (1988), Abstract.

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