Pharmaceutical compositions comprising hybrid .alpha.-interferon

Details Pharmaceutical compositions comprising hybrid .alpha.-interferon Pharmaceutical compositions comprising hybrid .alpha.-interferon

1994-08-10

1997-03-11

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Involving sex selection or contraception

424 854, 530351, A61K 3821, C07K 1452

Patent

active

056098685

ABSTRACT:
The present invention provides a stable aqueous solution of hybrid .alpha.-Interferon which contains as the stabilizer a buffer at a pH of from 3.0 to 5.0.

REFERENCES:
patent: 4847079 (1989-07-01), Kwan
Morehead et al. "Roles of the 29-138 Disulfide Bond of Subtype A of Human Interferon in its Antiviral Activity and Conformational Stability" Biochemistry 1984, vol. 23. (2500-2507) 1984.
H.K. Hochkeppel et al "Human Ien-Alpha Hybrids" Drugs of the Future vol. 17, No. 10 (1992.) pp. 899-914.
59196823 - Abstract of Japan.

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