Pharmaceutical compositions comprising fesoterodine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

Reexamination Certificate

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Details

C424S489000

Reexamination Certificate

active

07807715

ABSTRACT:
The present application relates to a pharmaceutical granulate comprising Fesoterodine or a pharmaceutically acceptable salt or solvate thereof and a pharmaceutically acceptable stabilizer, which can be selected from the group consisting of sorbitol, xylitol, polydextrose, isomalt, dextrose, and combinations thereof, and is preferably a sugar alcohol selected from the group consisting of xylitol and sorbitol. The granulate is suitable for incorporation into pharmaceutical compositions comprising a gel matrix formed by at least one type of hydroxypropyl methylcellulose into which the Fesoterodine is embedded and, optionally, further excipients. In certain embodiments, the granulate is formed by a process of wet granulation.

REFERENCES:
patent: 5204115 (1993-04-01), Olinger et al.
patent: 2005/0031685 (2005-02-01), Sen et al.
patent: 2005/0191352 (2005-09-01), Hayes et al.
patent: 2006/0018957 (2006-01-01), Lerner et al.
patent: 2008/0318982 (2008-12-01), Mastrell et al.
patent: 99/58478 (1999-11-01), None
patent: 01/35957 (2001-05-01), None

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