Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1997-03-06
1999-06-29
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424400, 514 11, 514937, 514938, A61K 9127, A61K 9107, A61K 3813
Patent
active
059165898
ABSTRACT:
Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or microemulsion form. The compositions typically comprise (1.1) a C.sub.1-5 alkyl or tetrahydrofurfuryl di- or partial-ether of a low molecular weight mono- or poly-oxy-alkane diol, e.g. Transcutol or Glycofurol, as hydrophilic component. Compositions are also provided comprising a cyclosporin and (1.1) and, suitably, also a saccharide monoester, e.g. raffinose or saccharose monolaurate. Dosage forms include topical formulations and, in particular, oral dosage forms.
REFERENCES:
patent: 3288824 (1966-11-01), Mahler et al.
patent: 3813345 (1974-05-01), Urton
patent: 3954967 (1976-05-01), Urton
patent: 4073943 (1978-02-01), Wretlind et al.
patent: 4146499 (1979-03-01), Rosano
patent: 4156719 (1979-05-01), Sezaki et al.
patent: 4388307 (1983-06-01), Cavanak
patent: 4567161 (1986-01-01), Posanski et al.
patent: 4695450 (1987-09-01), Bauer et al.
patent: 4719239 (1988-01-01), Muller et al.
patent: 4794000 (1988-12-01), Ecanow
patent: 4797272 (1989-01-01), Linn et al.
patent: 4797273 (1989-01-01), Linn et al.
patent: 4798823 (1989-01-01), Witzel
patent: 4835002 (1989-05-01), Wolf et al.
patent: 4888239 (1989-12-01), Brox
patent: 4914188 (1990-04-01), Dumont et al.
patent: 4963367 (1990-10-01), Ecanow
patent: 4990337 (1991-02-01), Kurihara et al.
patent: 4996193 (1991-02-01), Hewitt et al.
patent: 5037653 (1991-08-01), Dawson
patent: 5047396 (1991-09-01), Orban et al.
patent: 5154754 (1992-10-01), Damo et al.
patent: 5756450 (1998-05-01), Hahn et al.
Ulman's Encyclopaedia of Industrial Pharmacy, Vo. A9 (1987), pp. 298-299 and 308-311.
Carrigan et al., J. Pharm. Sci., 1973, vol. 62, pp. 1476-1479.
Frazer et al., J. Physiol. (1944) vol. 103, pp. 306-310.
95: 225610k, Anon. (1981).
Mizushima, 86-335072/51 (Jul. 26, 1985).
Takada, 87-024776/04 (Apr. 4, 1985).
Anon., Research Disclosure 21143 (Nov. 1981).
Beyer, et al., Phamazie in unserer Zeit, vol. 12(2): 55-60 (1983) (translation).
Bhargava, et al., Pharmaceutical Technology, Mar. 1987.
Cavanak and Sucker, Prog. Allergy vol. 38:65-72 (1986).
Ekman, S., Lipids 22: 657-663 (1987).
Jayakrishnan, et al., J. Soc. Cosmet. Chem. 34:335-350 (1983).
Muller, et al., Pharm. Ind. 50(3): 370-375 (1988) (translation).
Muller, et al., Pharm. Ind. 50(11): 1301-1306 (1988) (translation).
Remington's Pharmaceutical Sciences (17th ed.), Microemulsions, Chapter 20, pp. 298-299 (1985).
Reymond, et al., Pharmaceutical Research vol. 1 5(10): 673-767 (1988).
Reymond, et al., Pharmaceutical Research vol. 5(10): 677-679 (1988).
Ritschel, et al., Pharmaceutical Research vol. 5(10): Suppl. 108 (1988).
Ritchel, et al., Meth and Find Exp Clin Pharmacol. vol. 11(4): 281-87 (1989).
Stupar, et al., Goldschmidt Inforwist Essein, vol. 52: 22-28 (1982) (translation).
Takada, et al., J. Pharmacobio-Dyn. vol. 8: 320-323 (1985).
Takada, et al., J. Pharmacobio-Dyn. vol. 9: 156-160 (1986).
Takada, et al., J. Pharmaceutical Research vol. 3(1): 48-51 (1986).
Takada, et al., J. Pharmacobio-Dyn. vol. 11: 80-87 (1988).
Takada, et al., Int. of Pharmaceutics, vol. 44: 107-116 (1988).
Tarr, et al., Pharmaceutical Research, vol. 6(1): 40-43 (1989).
Yanagawa, et al., J. Microencapsulation 6(2): 161-164 (1989).
Ziegenmeyer, et al., Acta Pharmaceutica Technologica, vol. 26(4): 273-275 (1980) (translation).
Hahn, Biodegradable Tensides (1988) (translation).
Mubarak, Development and Testing of New Microemulsions (1982) (translation).
Pohler, Micro-Emulsion Gels Structural Investigations and Galenical Properties (1983) (translation).
Reymond, In Vitro In Vivo Model for the Absorption of Cyclosporin A (1986) (translation).
Hauer Birgit
Meinzer Armin
Posanski Ulrich
Richter Friedrich
Kishore Gollamudi S.
Mathias Marla J.
Novartis AG
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