Pharmaceutical compositions comprising cyclosporins

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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514 11, 514937, 514938, A61K 9127, A61K 9107, A61K 3813

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active

058661590

ABSTRACT:
Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or microemulsion form. The compositions typically comprise (1.1) a C.sub.1-5 alkyl or tetrahydrofurfuryl di- or partial-ether of a low molecular weight mono- or poly-oxy-alkane diol, e.g. Transcutol or Glycofurol, as hydrophilic component. Compositions are also provided comprising a cyclosporin and (1.1) and, suitably, also a saccharide monoester, e.g. raffinose or saccharose monolaurate. Dosage forms include topical formulations and, in particular, oral dosage forms.

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