Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1996-09-16
2000-05-16
Mertz, Prema
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
514 2, 514 8, 514 12, 514885, A61K 3817, A61K 3820
Patent
active
060633719
ABSTRACT:
The biological activity of exogenous ligand proteins is enhanced by intravenously co-administering to a mammal the ligand and a soluble receptor protein that binds thereto. Pharmaceutical compositions comprising a ligand protein complexed with a soluble receptor protein are provided. In certain embodiments, the ligand is selected from the group consisting of interleukins, colony stimulating factors, and tumor necrosis factor.
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Finkelman Fred D.
Maliszewski Charles R.
Anderson Kathryn A.
Immunex Corporation
Mertz Prema
The United States of America as represented by the Secretary of
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