Pharmaceutical compositions capable of increasing cerebral serot

Details Pharmaceutical compositions capable of increasing cerebral serot Pharmaceutical compositions capable of increasing cerebral serot

1982-09-16

1984-09-18

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

424253, 424266, 424319, A61K 3152, A61K 3170, A61K 31195, A61K 31455

Patent

active

044723873

ABSTRACT:
A pharmaceutical composition suitable for increasing cerebral serotonin concentration, comprising a serotonin precursor selected from the group consisting of 5-hydroxytryptophan and derivatives of 5-hydroxytryptophan having the formula: ##STR1## wherein R represent hydrogen; a C.sub.1 -C.sub.12 alkyl group; or a C.sub.5 -C.sub.16 alicyclic, monocyclic aromatic hydrocarbyl, or polycyclic aromatic hydrocarbyl group; and a nitrogenous heterocyclic compound selected from the group consisting of inosine, theophylline, theobromine, allopurinol, pyridoxine, hypoxanthine, folic acid, adenine, nicotinamide, caffeine, and orotic acid.

REFERENCES:
Martin Negwer, "Organisch-Chemische Arzneimittel und ihre Synonyma", 5e Edition, vol. II, 1978, Akademie-Verlag Berlin (DE), No. 6249, 5-Hydroxytryptophan.

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