Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-03-21
1977-01-25
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424263, 424331, A61K 31215
Patent
active
040052192
ABSTRACT:
Nitro-indane-diones, their production, and pharmaceutical compositions and their administration in forms suitable for the prophylaxis of asthma, hayfever and rhinitis in amounts effective for oral, parenteral and insufflation administration for such forms. The compounds are nitro-indane-diones of the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 have certain designated meanings, obtained by nitration of a parent un-nitrated compound and wherein ring A contains 1 or 2 double bonds.
REFERENCES:
patent: 3864493 (1975-02-01), Cairns et al.
patent: 3879544 (1975-04-01), Reisner et al.
patent: 3883653 (1975-05-01), Barth
patent: 3885038 (1975-05-01), Pfister et al.
Cema, et al., Chemical Abstracts, 68:87034q, (1968).
Severina, et al., Chemical Abstracts, 68:29304s.
Buckle Derek Richard
Smith Harry
Beecham Group Limited
Drezin Norman A.
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