Pharmaceutical compositions and methods of treatment of the corn

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 21, 514183, 514709, A61F 900

Patent

active

055805701

ABSTRACT:
Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.

REFERENCES:
patent: 3947478 (1976-03-01), Woods et al.
patent: 4436745 (1984-03-01), York, Jr.
patent: 4438272 (1984-03-01), York, Jr.
patent: 4454151 (1984-06-01), Waterbury
patent: 4474751 (1984-10-01), Haslam et al.
patent: 4559343 (1985-12-01), Han et al.
patent: 4599353 (1986-07-01), Bito
patent: 4600717 (1986-07-01), York, Jr.
patent: 4613587 (1986-09-01), Kessler
patent: 4665913 (1987-05-01), L'Esperance, Jr.
patent: 4686214 (1987-08-01), Boltralik
patent: 4692460 (1987-09-01), Carson
patent: 4717725 (1988-01-01), York, Jr.
patent: 4717727 (1988-01-01), Gunzler
patent: 4732148 (1988-03-01), L'Esperance, Jr.
patent: 4797422 (1989-01-01), Testa
patent: 4918105 (1990-04-01), Cartwright
patent: 4966911 (1990-10-01), Clark et al.
patent: 4983580 (1991-01-01), Gibson
patent: 5036056 (1991-07-01), Kludas
patent: 5098896 (1992-03-01), Muller
patent: 5112805 (1992-05-01), Salonen
patent: 5114953 (1992-05-01), Galardy
patent: 5149693 (1992-09-01), Cagle et al.
patent: 5149694 (1992-09-01), Cagle et al.
Taboada et al., Health Physics, vol. 40, pp. 677-683 (May 1981) "Response of the Corneal Epithelium to KrFExcimer Laser Pulses".
Del Pero et al., Human Excimer Laser Lamellar Refractive Keratectomy--A Clinical Study, ARVO Annual Meeting Abstract Issue, p. 281, No. 8 (1988).
Gaster et al., Excimer Laser Ablation and Wound Healing of Superficial Cornea in Rabbits and Primates, ARVO Annual Meeting Abstract Issue, p. 309, No. 4 (1988).
Tuft et al., Corneal Remodelling Following Anterior Keratectomy, ARVO Annual Meeting Abstract Issue, p. 310, No. 7 (1988).
Olsen et al., "The Effect of Steroids on the Healing of the Corneal Endothelim," Acta Ophthalmologica, 62, pp. 893-899 (1984).
Singh, "Corticosteroids in Corneal Endothelial Wound Healing," Annals of Ophthalmology, vol. 17, No. 4, pp. 238-243 (Apr. 1985).
Woost et al., "Effect of Growth Factors with Dexamethasone on Healing of Rabbit Corneal Stromal Incisions," Exp. Eye Res., 40, pp. 47-60 (1985).
K ossendrup et al., "Influence of Cyclosporin A, Dexamethasone, and Benzalkonium Chloride (BAK) on Corneal Epithelial Wound Healing in the Rabbit and Guinea Pig Eye," Cornea, 4, pp. 177-181 (1985/1986).
Sanchez et al., "Effect of Topical Steroids on the Healing of the Corneal Endothelim," Inves. Ophth., vol. 13, pp. 17-22 (Dec. 1974).
Barrandon et al., "Cell Migration Is Essential for Sustained Growth of Keratinocyte Colonies: The Roles of Transforming Growth Factor-.alpha. and Epidermal Growth Factor" Cell, vol. 50, pp. 1131-1137 (Sep. 25, 1987).
Lawrence et al., "The Reversal of an Adriamycin.COPYRGT. Induced Healing Impairment with Chemoattractants and Growth Factors" Annal. Surg., 203, pp. 142-147 (1986).
Fujikawa et al., "Fibronectin in Healing Rabbit Corneal Wounds", Laboratory Investigation, vol. 45, No. 2, pp. 120-128 (1981).
Ohashi et al., "Aldose Reductase Inhibitor (CT-112) Eyedrops for Diabetic Corneal Epitheliopathy," American Journal of Ophthalmology, vol. 105, No. 3 (Mar. 1988).
Fisher, "Intracellular Production of Oxygen-Derived Free Radicals," Proceedings of a Book Lodge Symposium, Apr. 1987.
Meister, "Selective Modification of Glutathione Metabolism," Science, vol. 220, pp. 472-477, (Apr. 1988).
Phan et al., "Regulation of Macrophage-Derived Fibroblast Growth Factor Release by Arachidonate Metabolites," Journal of Leukocyte Biology, 42: 106-113 (1987).
L'Esperance, Jr. et al., "Human Excimer Laser Keratectomy: Short Term Histopathology," Journal of Refractive Surgery, vol. 4, No. 4, pp. 118-124 (Jul./Aug. 1988).
Maxidex.RTM. product information, Physicians'Desk Reference for Ophthalmology, pp. 81-82 (1989).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Pharmaceutical compositions and methods of treatment of the corn does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical compositions and methods of treatment of the corn, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical compositions and methods of treatment of the corn will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-783358

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.