Pharmaceutical compositions and methods of sulphonamides contain

Details Pharmaceutical compositions and methods of sulphonamides contain Pharmaceutical compositions and methods of sulphonamides contain

1991-05-16

1992-12-22

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514822, A61K 3141

Patent

active

051735008

ABSTRACT:
The present invention provides sulphonamides of the general formula: ##STR1## wherein R is a hydrogen or halogen atom, a cyano group or a C.sub.1 -C.sub.6 -alkyl or trifluoromethyl radical, n is 1, 2 or 3, m is 0 or 1 to 5, X is a valency bond, an oxygen atom, a carbonyl group or a --CHOH-- group, A is a valency bond or a carbonyl group and B is a valency bond or an --NH-- group; the physiologically acceptable salts thereof with inorganic and organic acids, as well as the optical isomers thereof.
The present invention also provides processes for the preparation of these compounds and pharmaceutical compositions containing them.

REFERENCES:
Buchanan et al., J. Med. Chem., 16, pp. 174-175 (1973).

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