Pharmaceutical compositions and methods for use

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S318000, C514S343000, C546S133000, C546S187000, C546S276400, C546S279400, C544S111000

Reexamination Certificate

active

06890935

ABSTRACT:
The present invention relates to aryl olefinic azacyclic compounds and aryl acetylenic azacyclic compounds, including pyridyl olefinic cycloalkylamines and pyridyl acetylenic cycloalkylamines. The present invention also relates to prodrug derivatives of the compounds of the present invention.

REFERENCES:
patent: 5731323 (1998-03-01), Whittamore
patent: WO 0132264 (2001-05-01), None
Clementi et al.European Journal of Pharmacology, 393, 3-10, 2000.*
Cheng et al., “Synthesis and Binding of 6,7,9,9-tetrahydro-5H-pyrido[3,4-d]azepine and related ring-opened analogs at central nicotinic receptors”, J. Med. Chem., 34:177-190 (1999).

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