Pharmaceutical compositions and methods for preventing skin...

Details Pharmaceutical compositions and methods for preventing skin... Pharmaceutical compositions and methods for preventing skin...

2006-06-06

2006-06-06

Kim, Vickie (Department: 1618)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07056908

ABSTRACT:
Pharmaceutical compositions and methods for treating epithelial cancers and precancerous lesions employ indole carbazole compounds, such as staurosporine. Compositions containing these compounds are administered to a patient in an effective amount and may be administered topically.

REFERENCES:
Kiyoto, Itsumi, Inhibition of tumor promotion by staurosporine, a potent protein kinase C inhibitor., Keio Igaku, (abstract only) 1989, vol. 66(1), pp. 69-88.
Watanabe et al., Dual effects of staurosporine of arachidonic acid metabolism . . . (abstract only) Biochimica et Biophysica Acta, (1990), vol. 1047(2), pp. 141-147.
Yoshizawa et al., Tumor-promoting activity of staurosporine . . . , (abstract only), Cancer Research (1991) vol. 50(16), pp. 4974-4978.
Yamamoto et al., Differential inhibition by staurosporine, a potent protein kinase C inhibitor, . . . (abstract only) Carcinogenesis (1989), vol. 10(7), pp. 1315-1322.

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