Pharmaceutical compositions and methods for delivering...

Details Pharmaceutical compositions and methods for delivering... Pharmaceutical compositions and methods for delivering...

2011-07-19

2011-07-19

Schnizer, Richard (Department: 1635)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C435S459000, C514S04400A, C530S358000, C977S773000, C977S906000, C977S916000

Reexamination Certificate

active

07981446

ABSTRACT:
The present invention relates to methods of delivering nucleic acids into cells using a nucleic acid binding molecule containing a multimeric or spacer-incorporated protein transduction domain (PTD). The invention also relates to novel compositions that contain a nucleic acid complexed or conjugated with a nucleic acid binding molecule. The nucleic acid binding molecule may contain a multimeric or spacer-incorporated PTD, and may further contain a nucleic acid binding region. The nucleic acid complexes or conjugations of the present invention may be employed to inhibit expression of a target gene, and/or determine the function of a target gene.

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