Pharmaceutical compositions and method of treatment employing 1,

Details Pharmaceutical compositions and method of treatment employing 1, Pharmaceutical compositions and method of treatment employing 1,

1974-07-31

1976-06-29

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

260308D, 424275, A61K 3119

Patent

active

039669661

ABSTRACT:
[1,3-Dioxo-2-substituted and 2,2-disubstituted-indanyloxy(or thio)]alkanoic acids and their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. The acid products are prepared by treating a (2- or 2,2-di)substituted-6-hydroxy-(or mercapto)-1,3-indanedione with a haloalkanoic acid or ester thereof and if the ester is employed hydrolyzing the ester.

REFERENCES:
patent: 3704314 (1972-11-01), Cragoe, Jr.

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