Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

1980-06-26

1985-08-13

Goldberg, Jerome D.

Drug, bio-affecting and body treating compositions

Plural fermentates of different origin

A61K 3500

Patent

active

045349681

ABSTRACT:
A synergistic combination is produced which comprises a synergistically effective amount of clavulanic acid or a pharmaceutically acceptable salt thereof and an antibacterially effective amount of a compound of the formula (II): ##STR1## or a pharmaceutically acceptable salt thereof wherein R.sup.1 is hydrogen, hydroxyl or acetoxyl, R.sup.2 is methyl and R.sup.3 is CO.R.sup.4 wherein R.sup.4 is phenyl, isobutyl, furyl, thienyl or NHCH.sub.3 or R.sup.2 is joined to R.sup.3 so that NR.sup.2 R.sup.3 is an imidazolin-2-on-1-yl.

REFERENCES:
Chemical Abstracts 77: 126629v, (1972).
Chemical Abstracts 81: 63616y, (1974).
Derwent Farm Doc. #72840/w/44/, Abstracting DT 2517316, published 10/23/75.

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