Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

1990-12-05

1993-07-20

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424472, 424464, A61K 932

Patent

active

052291340

ABSTRACT:
Delayed-release oral dosage forms are described comprising cimetidine or a salt thereof and optionally a buffer that is capable of aiding dissolution of cimetidine in the intestine, coated with a release-delaying substance comprising a coating agent such as Eudragit.RTM. L 30 D.

REFERENCES:
patent: 4851228 (1989-07-01), Zentner et al.
patent: 4871549 (1989-10-01), Ueda et al.
patent: 4940588 (1990-07-01), Sparks et al.
patent: 4952402 (1990-08-01), Sparks et al.
patent: 4968507 (1990-11-01), Zentner et al.
patent: 4976949 (1990-12-01), Meyer et al.
Conte, et al., Il. Farmaco, vol. 39, No. 3, Mar. 1984.
Ortega et al., Current Therapeutic Research 28(5): 692-697 (1980).
Conti et al., Folia Med., 84(5), 407 (1982)-English translation attached.
Speigl et al., Sci. Pharm., 51, 215-218 (1983)-English translation attached.
Hillebrand, Wien Me. Wochenschrift, 135, 191 (1985)-English translation attached.
Maysinger et al., International Journal of Pharmaceutics, 17, 129-134 (1983).
Marenco et al., Panminerva Medica, 27, pp. 182-187 (1985).

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