Pharmaceutical compositions

Details Pharmaceutical compositions Pharmaceutical compositions

1997-02-24

1998-12-29

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424400, 424464, 424489, 424491, A61K 900, A61K 920, A61K 914

Patent

active

058537481

ABSTRACT:
Compositions containing a bile salt and a buffer such as a carbonate or bicarbonate salt which is adapted to buffer the gut to a pH of from 7.5 to 9 are capable of increasing the bioavailability of an active molecule whilst minimising the toxic side effects which are generally associated with bile salts.

REFERENCES:
Wosiewitz et al., J. Hepatology, 14:7-15(1992).
Wosiewitz et al., Chemical Abstracts, vol. 116, #143793 1992.
Kakemi et al., Chem. Pharm. Bull., 18(2:275-280 (1970).
Kojima et al., Chem. Pharm. Bull., 25(6):1243-1248 (1977).

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