Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1979-10-09
1981-10-13
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424244, 424250, A61K 3133, A61K 31155, A61K 31495
Patent
active
042948541
ABSTRACT:
S-(Aminoalkyl)isothioureas which have immunosuppressant activity. Two specific compounds are 2-(3-dimethylaminopropylthio)-2-imidazoline and N,N'-dimethyl-S-(3-dimethylaminopropyl)isothiourea.
REFERENCES:
patent: 2648710 (1953-08-01), Morrison et al.
patent: 4152453 (1979-05-01), Durant et al.
Ozawa et al., Yakugaku Zasshi 88(6): 747-754 (1968).
Durant Graham J.
Ganellin Charon R.
Vickers Margaret R.
Foggio Richard D.
Friedman Stanley J.
Keps Joan S.
Lourie Alan D.
Smith Kline & French Laboratories Limited
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