Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-01-25
1984-01-10
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424251, A61K 31505, A61K 3152
Patent
active
044253460
ABSTRACT:
The present invention relates to pharmaceutical compositions adapted for topical administration to the eye and to their preparation and use. More specifically this invention relates to anti-glaucoma ophthalmic compositions containing tetraazabicyclic compounds of the formula: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, X and Y are hereinafter defined and to the preparation and use of such compositions.
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patent: 4285947 (1981-08-01), Higuchi et al.
Martindale-The Extra Pharmacopoeia, 27th Ed. (1977) pp. 569-570.
Pteridines XII Structure-Activity Relationships of Some Pteridine Diuretics, Weinstock et al., J. Med. Chem. 1968 11 573-579.
2,4,7-Triamino-6-Ortho-Substituted Aryl Pteridines, A New Series of Potent Antimalarial Agents, Osdene et al., J. Med. Chem. 1967 10 pp. 431-433.
Robinson Douglas W.
Smith and Nephew Associated Companies Limited
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