Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2005-11-08
2005-11-08
Spear, James M. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S435000, C424S436000, C424S451000, C424S458000, C424S464000, C424S465000, C424S466000, C424S467000, C424S468000, C424S474000, C424S479000, C424S489000, C424S490000, C424S494000, C424S497000
Reexamination Certificate
active
06962717
ABSTRACT:
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble in gastric and intestinal juices, where the particles have as core a homogeneous mixture comprising an active pharmaceutical ingredient and a polymer insoluble in gastric and intestinal juices, with an average internal pore diameter not exceeding 35 μm, makes efficient and pH-independent delaying of release possible even with comparatively small amounts of polymer. It is additionally distinguished by a long shelf life and is particularly suitable also for nonspherical particles.
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Gruber Peter
Huber Gerald
Disphar International B.V.
Leydig , Voit & Mayer, Ltd.
Spear James M.
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