Pharmaceutical composition useful for inhibiting platelet aggreg

Details Pharmaceutical composition useful for inhibiting platelet aggreg Pharmaceutical composition useful for inhibiting platelet aggreg

1985-02-15

1986-11-04

Moyer, Donald B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514822, A61K 3170

Patent

active

046210768

ABSTRACT:
A pharmaceutical composition comprising an amount, effective for inhibiting platelet aggregation, of guanosine monophosphate represented by the following formula ##STR1## wherein one of X, Y and Z represents a H.sub.2 PO.sub.3 group and the remaining two of these represent a hydrogen atom,
or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable diluent or carrier.

REFERENCES:
Packham et al. Am. J. Physiol., vol. 227, No. 5 1974, pp. 1143-1148.
Maguire et al. Experientia, vol. 30, No. 8 1974, pp. 922-924.
Nikulin, A. A., Cited in Chem. Abstracts, vol. 89 1978, 3687c.
The Merck Index, 9th ed. 1976, p. 594, #4421, 4422.

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