Pharmaceutical composition that exhibits reduced...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S267000, C514S274000

Reexamination Certificate

active

06838469

ABSTRACT:
Pharmaceutical compositions that exhibit reduced gastrointestinal side-effects comprising a known active substance having antitumor effects selected from the group consisting of pyrimidine derivatives, or a pharmaceutically acceptable acid addition salt thereof, and O-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime, or a pharmaceutically acceptable acid addition salt thereof, are disclosed.

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patent: 5278309 (1994-01-01), Bertok et al.
patent: 6143741 (2000-11-01), Jednakovits et al.
patent: WO9713504 (1997-04-01), None
Watson S.A. et al, BIODRUGS, (1998), 9/4, (325-335).
Carter et al., Chemotherapy of Cancer, Second Edition, John Wiley & Sons, N.Y., N.Y., pp. 107-108, (Aug. 1981).

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