Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases
Patent
1986-06-30
1988-07-05
Rollins, John
Drug, bio-affecting and body treating compositions
Enzyme or coenzyme containing
Hydrolases
424 9464, 424 9466, 514255, A61K 3754, A61K 3755, A61K 31495
Patent
active
047553839
ABSTRACT:
A pharmaceutical composition is disclosed which comprises a physiologically active substance possessing peptide bonds in its structure and being inactivable by digestive enzymes, the active substances being other than insulin, and a synthetic chymotrypsin inhibitor. The composition is particularly suitable for intestinal absorption of the active substance.
REFERENCES:
Chem. Abst. 100:209820m, 1984.
Chemical Abstracts, vol. 95, No. 24, Dec. 14, 1981, p. 378, ref. No. 209657a, "Readily Absorbable Enzyme Pharmaceuticals", (KOWA Co. Ltd).
Chemical Abstracts, vol. 94, No. 21, May, 25, 1981, p. 689, "Hydroxybenzoic Acid Derivatives" (KOWA Co. Ltd.).
Chemical Abstracts, vol. 96, No. 21, May 24, 1982, p. 681, ref. No. 180955d, "Phenyl Esters", (KOWA Co., Ltd.).
Chemical Abstracts, vol. 99, No. 5, Aug. 1, 1983, p. 561, ref. No. 38809c, "Phenyl Esters", (KOHJIN Co., Ltd.).
Journal of Biochemistry, vol. 95, No. 2, Feb. 1984, pp. 319-322, S. Fujii et al., "New Synthetic Inhibitors of Chymotrypsin".
European Search Report, Aug. 19, 1987.
Fujii Setsuro
Ikegaya Kouji
Nagakura Masahiko
Yokoo Nobuo
Yokoyama Touru
Kowa Co. Ltd.
Rollins John
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