Pharmaceutical composition of nanoparticles for protein drug...

Details Pharmaceutical composition of nanoparticles for protein drug... Pharmaceutical composition of nanoparticles for protein drug...

2011-04-04

2011-11-01

Monshipouri, Maryam (Department: 1656)

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

C424S001730

Reexamination Certificate

active

08048404

ABSTRACT:
The invention discloses a pharmaceutical composition of bioactive nanoparticles composed of chitosan, poly-glutamic acid, and a bioactive agent for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.

REFERENCES:
patent: 6649192 (2003-11-01), Alonso Fernandez et al.
patent: 6726934 (2004-04-01), Prokop
Nam et al., Bioconjugate Chemistry, 21(4), 578-582.
Thanou M et al. “Chitosan and its derivatives as intestinal absorption enhancers” Adv. Drug Deliv. Rev. 2001;50:S91-S101.

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