Pharmaceutical composition of nanoparticles

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound

Reexamination Certificate

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C424S001730

Reexamination Certificate

active

08007768

ABSTRACT:
The invention discloses a pharmaceutical composition of the nanoparticles composed of chitosan, a negatively charged substrate, a transition metal ion, and at least one bioactive agent for drug delivery. The nanoparticles are characterized with a positive surface charge configured for promoting enhanced permeability for bioactive agent delivery.

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Vila A et al. “Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice” Eur J Pharma and Biopharma 2004;57:123-131.

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