Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-12-14
1994-05-31
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514336, 514345, 514424, 514456, 514457, 514337, A61K 3144, A61K 3153, A61K 3135
Patent
active
053170296
ABSTRACT:
Pharmaceutical compositions for the inhibition of bone resorption comprising a pharmaceutical carrier and a therapeutically effective amount of a benzopyran derivative represented by the general formula (I) ##STR1## wherein the broken-lined bond denotes an optional double bond, R.sub.1 denotes a hydrogen atom or a hydroxyl group, R.sub.2 denotes a cyano group, a phenylsulfonyl group or a halogen-substituted methoxyl group, and R.sub.3 denotes a group having the formula ##STR2## Since they inhibit bone resorption, they are useful for the treatment and prevention of diseases associated with bone metabolism.
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Paciorek et al., J. Cardiovasc. Pharmacol., vol. 15, No. 2, pp. 188-197, 1990
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Carniato Denis
Englert Heinrich
Inazu Mizuho
Inoue Tsutomu
Katoh Masakazu
Criares T. J.
Hoechst Japan Limited
Waddell Frederick E.
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