Pharmaceutical composition for treating transplanted tumor cells

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 3142

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active

045073090

ABSTRACT:
A treating agent whose effective ingredient is an anthranyl derivative of the formula: ##STR1## (wherein R.sub.1 and R.sub.2 may be the same or different and represent a hydrogen atom, a hydroxyl group, a lower alkoxy group, preferably C.sub.1 -C.sub.3 alkoxy group, a lower alkyl group, preferably C.sub.1 -C.sub.3 alkyl group, a nitro group or a halogen atom) is disclosed.

REFERENCES:
Davis R. B. et al., "Condensation of Aromatic Nitro Compounds with Acrylacetonitriles. II. Some p-Substituted Nitrobenzenes", J. Org. Chem., 25, 1884-88, (1960).
Tanasescu, I. et al., "Sur les Acridones (XIX). Syntheses et Comportements de Certaines Bromoacridones Substituees", Bull. Chim. France, 693-96, (1960).
Tanasescu, I. et al., "Sur les Acridones (X) (1) p.Chlorophenylanthranile et Chloro-3-Acridone", Bull. Chim. France, 3, 2383-85, (1936).
Tanasescu, I. et al., "Sur la Condensation des o-Nitrobenzaldehydes Avec l'Aniline (III) (1). Comportement Photophimique des Anthraniles et Triphenylmethanes Obtenus", Bull. Chim. France, 4, 245-258, (1937).
Guyot, A. et al., "Sur le Produit de la Combinaison de l'Aldehyde Ortho-Nitrobenzoique Avec le Phenol en Presence d'Acide Chlorhydrique", Bull. Chim. France, 31, 530-533, (1904).
Simpson, J. C. E. et al., "58. Cinnolines. Part I. Some New Examples", J. Chem. Soc., 353-58, (1942).
Leiter et al., Cancer Research, Part 2, vol. 24, No. 6, Jul. 1964, pp. 880-887, 891, 895 and 1034, (No. 56311).

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