Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2011-06-28
2011-06-28
Gussow, Anne M. (Department: 1643)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S395000
Reexamination Certificate
active
07968514
ABSTRACT:
The invention relates to therapeutic and prophylactic treatment of ovarian cancer and metastases thereof. More specifically, the invention relates to immunogenic polypeptides comprising at least a portion of an ovarian tissue cell-associated protein or immunologically active variants thereof and to nucleic acids encoding such polypeptides and to the use thereof in immunotherapeutic methods of treatment. Said immunogenic polypeptides are provided by the zona pellucida (ZP) glycoproteins. ZP glycoproteins and fragments thereof that can induce a CD8+and/or CD4+T cell response as well as nucleic acid sequences encoding them can suitably be used in the present immunotherapeutic strategies.
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Bennink Herman Jan Tijmen Coelingh
Visser Monique
Browdy and Neimark PLLC
Gussow Anne M.
Pantarhei Bioscience B.V.
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