Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1982-01-25
1983-09-27
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Dentifrices
424 54, 424 55, A61K 716, A61K 722, A61K 724
Patent
active
044068824
ABSTRACT:
The present invention provides a water-soluble or water-dispersible particulate pharmaceutical composition comprising, per one part by weight of glycyrrhetinic acid and/or glycyrrhetinic acid derivative (as hereinbefore defined), 10 to 100 parts by weight of lactose and/or sorbitol, 10 to 50 parts by weight of at least one buffer selected from sodium citrate, potassium citrate, sodium tartrate, potassium tartrate, sodium malate and potassium malate and 0.1 to 10 parts by weight of disodium edetate.
REFERENCES:
patent: 3944660 (1976-03-01), Gottfried et al.
A.D.A. Accepted Dental Therapeutics 38th ed. Sep. 1979, American Dental Assocation Chicago, Ill. (Posl#RK 701 A3), pp. 15-16, 48-50, 249-256, 262-269, 279-280, 339-347.
Tamura et al., Chem. Abstr. 95: 108560h (1981) of Shika Kiso Igakkai Zasshi (1981) 23 (1):1-8, Glycynhrrhetinic Acid Ointment for Stomatitis on Oral Mucosa.
Dedieu et al., Chem. Abstr. 94: 361322 (1981) of Brit 1,567,307 May 14, 1980., Mouthwashes of Ammonium Glycyrrhizinate.
Hashimoto et al., Chem. Abstr. 92: 116267n (1980) of Jpn. Kokai Tokkyo Koho 79-117040 Glycyrrhetic Acid Monoammonium Salt in Dentifrices.
Sato et al., Chem. Abstr. 91: 9357h 1979 of Jpn. Kokai Tokkyo Koho 79 26339 Glycyrrhizic Acid or Salts, Di-K Glycyrrhizate in Dentifrices.
Edgar et al., Chem. Abstr. 89: 141063x (1978) of J. Dent Res. (1978) 57 (1): 59-64 Reduction in Enamel Dissolution by Licorice and Glycyrrhizinic Acid.
Takahashi et al., Chem. Abstr. 86: 8582n (1977) of Japan Kokai 7641447 Stearyl Glycyrrhetinate in Dentifrices.
Beriou Chem. Abstr. 84: 49819x (1976) of Brit. 1,393,498 Ammonium Glycyrrhizate in Toothpaste.
Villette Chem. Abstr. 83: 65467r (1975) of Fr. Demande 2225146 Ammonium Glycyrrhizate in Dentifrice.
Veyron et al., Chem. Abstr. 76: 158370Z (1972) of Fr. CAM 222 Addn. to Fr. M 1306 Bucco Dental Inflammatory Disorders Treated with Dentifrices, Elixir sets of .beta.-Glycyrrhetinic Acid.
Simson Chem. Abstr. 69: 99406w (1968) of Brit. 1,124,976 Mouth Ulcers Treated with DI-NA Glycyrrhetinic Acid Hemisuccinate.
Baxendale Lily
Turner John C.
Biorex Laboratories Limited
Rose Shep K.
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