Pharmaceutical composition for treating cancer

Details Pharmaceutical composition for treating cancer Pharmaceutical composition for treating cancer

2008-09-19

2010-06-29

McGarry, Sean (Department: 1635)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C536S023100, C536S024300, C536S024330, C536S024500

Reexamination Certificate

active

07745419

ABSTRACT:
The present invention provides a small interfering RNA (siRNA) that is capable of inhibiting intracellular expression of Wnt1 through complementary binding to a Wnt1 transcript (mRNA transcript) base sequence and a pharmaceutical composition for treating cancer comprising the same. siRNA of the present invention which is complementary to a base sequence of a Wnt1 transcript (mRNA) provides apoptotic cancer cell death due to inhibition of expression of Wnt1 commonly expressed in cancer cells, by RNA-mediated interference (RNAi). Therefore, the composition of the present invention comprising the same can be used as an excellent anticancer drug.

REFERENCES:
patent: 2004/0247593 (2004-12-01), He et al.
Nguyen et al. (Current Opinion in Molecular Therapeutics, 2008 vol. 10(2):158-167.
Lu et al. (2005) in RNA Interference Technology (Cambridge, Appasani, ed.).
Samarsky et al. in RNA Interference Technology, (2005) (Cambridge, Appasani, ed.) pp. 389-394.
Downward, J. (BMJ, 2004 vol. 328:1245-1428).

Affiliated with

Also associated with

Rating

Pharmaceutical composition for treating cancer does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical composition for treating cancer, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical composition for treating cancer will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4195484