Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1998-06-05
1999-07-27
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
514458, 514559, A61K 3159, A61K 31355, A61K 3120
Patent
active
059290579
ABSTRACT:
9-Cis-retinoic acid-.alpha.-tocopherol esters, pharmaceutical compositions containing the same and use of the same as a medicine for the treatment of leukemia, in particular, the remission of leukemia are provided and a combined use of a 9-cis-retinoic acid-.alpha.-tocopherol ester and either 1.alpha.,25-dihydroxyvitamin D.sub.3 or 9-cis-retinoic acid exhibits a synergistic effect in the treatment of leukemia without any side effects caused by 1.alpha.,25-dihydroxyvitamin D.sub.3 or 9-cis-retinoic acid.
REFERENCES:
patent: 3878202 (1975-04-01), Fukawa et al.
Honma Yoshio
Inomata Kohei
Kanatani Yasuhiro
Kishiye Takao
Makishima Makoto
Goldberg Jerome D.
Nisshin Flour Milling Co. Ltd.
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