Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1985-07-15
1986-08-19
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Dentifrices
514529, 514557, 514835, A61K 716, A61K 31215, A61K 3119
Patent
active
046069119
ABSTRACT:
A pharmaceutical composition for the prevention of dental caries which comprises as essential component(s) one or more of pentacyclic acid triterpenes of the formula: ##STR1## wherein R.sub.1 represents CH.sub.3, CHO or CH.sub.2 OH, R.sub.2 and R.sub.3 independently represent CH.sub.3 or COOH, R.sub.4 represents H, CH.sub.3, COOH or COOCH.sub.3, R.sub.5 and R.sub.6 independently represent H, CH.sub.3 or OH, and A represents two Hs or O, and their salts.
REFERENCES:
patent: 3328246 (1967-06-01), Gottfried et al.
patent: 4022881 (1977-05-01), Hawking
patent: 4173648 (1979-11-01), Pifferi et al.
J. of Med. Chemistry 17(2), 191-194, (1974)-Pitzele.
Hayashi Shin'ichi
Kametaka Shigeru
Koike Tetsuo
Yoshida Akiyoshi
Robinson Douglas W.
Rohto Pharmaceutical Co. Ltd.
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