Pharmaceutical composition for the preparation of a stable powde

Details Pharmaceutical composition for the preparation of a stable powde Pharmaceutical composition for the preparation of a stable powde

1994-01-04

1995-08-01

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424452, 424489, 514159, A61K 914, A61K 948, A61K 3160, A61K 31165

Patent

active

054378745

ABSTRACT:
A novel pharmaceutical composition for the preparation of a stable powder containing an association of acetylsalicylic acid and metoclopramide as the active ingredients. The acetylsalicylic acid is in the form of a water soluble salt or complex and is in association with metoclopramide or a pharmaceutically acceptable salt thereof and at least one pharmaceutically acceptable hydrophilic polymer in an amount sufficient to stabilize the metoclopramide. This composition has remarkable stability in powder form and can be used to prepare sachets for the treatment of migraine.

REFERENCES:
patent: 4325971 (1982-04-01), Poyser et al.
patent: 4380540 (1983-04-01), Poyser et al.
patent: 5273759 (1983-12-01), Simmons
patent: 5306506 (1994-04-01), Zema et al.

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