Pharmaceutical composition for oral administration containing co

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis

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Details

424177, 424199, 424365, A61K 3514

Patent

active

043483844

ABSTRACT:
A pharmaceutical composition suitable for the treatment and prophylaxis of hemophilia A or B, which comprises coagulation factor VIII or IX and a protease inhibitor (particularly aprotinin) which are incorporated in liposomes and optionally lyophilized and/or encapsulated in intestine capsules. The composition can give high absorption of the required coagulation factor from intestinal tract without being decomposed in gastrointestinal tract even by administration in oral route.

REFERENCES:
patent: 4183960 (1980-01-01), Asher et al.

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