Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1981-10-07
1982-09-07
Rosen, Sam
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
424177, 424199, 424365, A61K 3514
Patent
active
043483844
ABSTRACT:
A pharmaceutical composition suitable for the treatment and prophylaxis of hemophilia A or B, which comprises coagulation factor VIII or IX and a protease inhibitor (particularly aprotinin) which are incorporated in liposomes and optionally lyophilized and/or encapsulated in intestine capsules. The composition can give high absorption of the required coagulation factor from intestinal tract without being decomposed in gastrointestinal tract even by administration in oral route.
REFERENCES:
patent: 4183960 (1980-01-01), Asher et al.
Horikoshi Isamu
Sakuragawa Nobuo
Takahashi Kaoru
Ueno Masaharu
Dainippon Pharmaceutical Co., Ltd.
Rosen Sam
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