Pharmaceutical composition for diabetic nephropathy

Drug – bio-affecting and body treating compositions – Natural resin – gum – or balsam as active ingredient

Reexamination Certificate

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Reexamination Certificate

active

06884421

ABSTRACT:
The present invention provides a synergistic pharmaceutical composition of butyric acid wheat fiber bran and guar gum and a method of treatment for diabetic nephropathy.

REFERENCES:
patent: 4968694 (1990-11-01), Madsen et al.
patent: 5789393 (1998-08-01), Dressman et al.
patent: 2002027941 (2002-12-01), None
Cameron-Smith, D et al., “Dietary Guar Gum Improves Insulin Sensitivity in Streptoszotocin-Induced Diabetic Rats,” The Journ of Nutrition: Feb. 1997, 127, 2, pp. 359-364.*
Nandini, C. D. etal., “Effect of Dietary Fibre on Intestinal and Renal Disaccharidases in Diabetic Rats,” Nutrition Research, Elsevier Science, 2000, vol. 20, No. 9, pp. 1301-1307.*
Kumar, C.M. et al., “Modulatory effect of butyric acid-a product of dietary fiber fermentation in experimentally induced diabetic rats,” Journal of Nutritional Biochemistry 13, (2002) pp. 522-527.*
Chethankumar, M. et al., “Butyric acid modulates activities on intestinal and renal disaccharidases in experimentally induced diabetic rats,” Nahrung/Food, 46 (2002) No. 5, pp. 345-348.*
Gallaher, D.D. et al., “Dietary guar gum halts further reanl enlargement in rats with established diabetes,” Journal of Nutrition, 1992 Dec.;122(12):2391-2397.

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