Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2007-01-02
2007-01-02
Kim, Vickie (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S468000, C424S465000
Reexamination Certificate
active
10172125
ABSTRACT:
The present invention describes a novel controlled release multilayer composition that is capable of delivering a first active agent from one layer immediately followed by continuous controlled delivery of second active agent from matrix forming layer while the dosage form floats and is retained in the fluid of the environment. The floating bilayer system comprises of immediate release layer containing one active agent and a disintegrating agent whereas second floating matrix forming layer comprises a gas generating component, a gelling agent, and a second active agent. The present invention relates more particularly to a controlled release fluoroquinolone compositions, which maintain a therapeutically effective blood concentration of fluoroquinolone for duration with once a day administration.
REFERENCES:
patent: 4140755 (1979-02-01), Sheth et al.
patent: 6049177 (2000-04-01), Felper
patent: 6753011 (2004-06-01), Faour
patent: 2003/0104052 (2003-06-01), Berner et al.
Doshi Madhukat Mansukhlal
Joshi Milind Dattatraya
Mehta Bharat Pravinchandra
J.B. Chemicals & Pharmaceuticals Ltd.
Kim Vickie
Lackenbach & Siegel LLP
Nissen J. Harold
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