Pharmaceutical composition containing interferon in stable state

Details Pharmaceutical composition containing interferon in stable state Pharmaceutical composition containing interferon in stable state

1984-01-04

1987-06-23

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

435811, A61K 4502

Patent

active

046751840

ABSTRACT:
A pharmaceutical composition for treating viral diseases, such as pasta, gargle, gel, ointment, suppository, spray, etc., containing interferon in a stable state which comprises an effective amount of human interferon, 15 to 60% by weight of a tri or higher polyhydric sugar alcohol and an organic acid buffer as stabilizers, and a conventional pharmaceutical carrier or diluent. The pH of the composition is about 3 to 6. Optionally, the composition can further contain as a stabilizer an anionic surfactant and/or albumin.

REFERENCES:
patent: 3981991 (1976-09-01), Stewart et al.
patent: 4100150 (1978-07-01), Cartwright
patent: 4137307 (1979-01-01), Funakoshi et al.
patent: 4252791 (1981-02-01), Grossberg et al.
International Publication No. WO83/0119, Publication Date 4/14/83.

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