Pharmaceutical composition containing cyclosporin in admixture w

Details Pharmaceutical composition containing cyclosporin in admixture w Pharmaceutical composition containing cyclosporin in admixture w

1990-09-21

1991-09-24

Doll, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 9, 514885, A61K 3702

Patent

active

050514024

ABSTRACT:
Cyclosporins are useful immunosuppressive, anti-fungal and antiphlogistic agents which are relatively insoluble in water and aqueous fluids (including body fluids). They may be rendered more soluble by the concomitant administration of .alpha.-cyclodextrin, either separately, but essentially simultaneously or, preferably, in admixture.

REFERENCES:
patent: 4117118 (1978-09-01), Harri et al.
patent: 4388307 (1983-06-01), Cavanak
Stadler-Szoke et al., Proceedings of the First Int. Symp. on Cyclodextrins, Szejtli (ed.), D. Reidel Publishing Co., Boston, U.S.A., pp. 377-388 (1981).
Merck Index, 10th Edition, 1983, p. 396, No. 2748.

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